Motlalepula Gilbert Matsabisa

Prof. Motlalepula Gilbert Matsabisa, Professor of Pharmacology and Director of Indigenous Knowledge Systems at the University of the Free State.

Motlalepula Gilbert Matsabisa

Motlalepula Gilbert Matsabisa, PhD, is a distinguished Professor of Pharmacology and the Director of the Indigenous Knowledge Systems (IKS) Health Lead Programme at the University of the Free State, South Africa. He stands at the forefront of scientifically validating and integrating African Traditional Medicines into contemporary healthcare systems. His leadership extends globally through influential roles with the World Health Organization and as a key driver of South-South collaboration, particularly in establishing the BRICS Natural Medicines Institute.

Professor Matsabisa’s work embodies the spirit of the 3rd WCTCIM by championing evidence-based traditional knowledge, shaping regulatory policy, and fostering international partnerships to advance global public health. Consequently, his expertise provides invaluable insights for the congress.

ORCID Profile: https://orcid.org/0000-0003-2921-8882


Biography and Expertise of Motlalepula Gilbert Matsabisa

Professor Motlalepula Gilbert Matsabisa is a leading authority in pharmacology and a passionate advocate for integrating Indigenous Knowledge Systems into modern medicine. As Director of the IKS Programme at the University of the Free State, he has built a robust platform for the research, development, and commercialization of African Traditional Medicines. His work is characterized by a commitment to rigorous scientific methodology to validate the safety and efficacy of traditional remedies used for generations across Africa.

His expertise directly aligns with the 3rd WCTCIM’s Thematic Axis, “Integration of TCIM into Healthcare Systems.” Professor Matsabisa actively shapes this integration through his advisory roles for the South African Health Products Regulatory Authority (SAHPRA) and the World Health Organization (WHO). Furthermore, his leadership in creating a regulatory framework for African Traditional Medicines exemplifies the principles of the Gujarat Declaration, which call for evidence-based policies. His efforts in championing “Knowledge Diversity,” a pillar of the congress motto, are evident in his dedication to ensuring African pharmacopeia receives global recognition and respect.

Beyond national borders, the influence of Motlalepula Gilbert Matsabisa is profound. He is a central figure in promoting South-South collaboration, a cornerstone of this historic WCTCIM in Latin America. His pioneering work to establish the BRICS Natural Medicines Institute highlights his vision for a global health landscape where traditional knowledge from the Global South contributes to creating healthier, more resilient “Well-being Societies.” His participation brings a vital perspective on leveraging traditional medicine for sustainable global health solutions.

Academic Foundation and Mentorship

The academic foundation of Professor Motlalepula Gilbert Matsabisa is rooted in the rigorous discipline of Pharmacology, culminating in a PhD. This deep scientific training provides him with the essential tools to investigate, validate, and understand the mechanisms of action of traditional herbal medicines. His approach is not merely to accept traditional claims but to subject them to the highest standards of scientific scrutiny, thereby building a credible evidence base that can be accepted by the global medical community.

However, his contribution to academia extends far beyond his own qualifications. A significant part of his legacy is his commitment to fostering the next generation of scientists, a role that directly supports the WCTCIM’s Thematic Axis on “TCIM Education and Training.” He has created a vibrant and productive academic environment where young researchers are trained to navigate the complex intersection of traditional knowledge and modern science. This mentorship ensures the sustainability and continued growth of the field.

  • Doctor of Philosophy (PhD) in Pharmacology: The pinnacle of his formal academic training, providing the expertise for his life’s work.
  • Extensive Student Supervision: He has successfully guided and graduated a remarkable number of students, including:
    • Over 40 Honours students
    • Over 30 Master of Science (MSc) students
    • Over 10 Doctor of Philosophy (PhD) students
    • Over 30 Postdoctoral Research Fellows, with 18 currently under his supervision.

Pioneering Research and Innovation

Professor Motlalepula Gilbert Matsabisa is a prolific researcher and innovator whose work translates directly into tangible health solutions. He has established sophisticated clinical trial platforms specifically designed to evaluate the claims associated with traditional medicines. A notable example is the joint clinical trial he leads with the Beijing University of Chinese Medicines to investigate treatments for long COVID-19, a project that showcases his commitment to addressing contemporary global health crises through international collaboration.

His research is not confined to clinical validation; it also encompasses fundamental drug discovery. This is powerfully demonstrated by his patent on seven novel compounds isolated from a medicinal plant, which show promising antimalarial action. This achievement represents a significant contribution to the fight against a major infectious disease and aligns with the congress axis on “Contributions of TCIM to Global Public Health.” Beyond discovery, Motlalepula Gilbert Matsabisa focuses on the entire value chain, from formulation and quality control to manufacturing and packaging, ensuring that promising research evolves into accessible products.

Furthermore, his work extends to community empowerment. He actively runs projects that train indigenous communities in entrepreneurship, helping them to create sustainable enterprises based on medicinal plants. This approach not only preserves traditional knowledge but also creates economic opportunities, directly contributing to the development of “Well-being Societies.” His successful trademarking of immune modulators, indigenous teas, and cannabis product prototypes underscores his ability to bridge scientific research with market-ready innovation.

Connect with Prof. Matsabisa

To further explore the impactful research, policy work, and academic leadership of Professor Motlalepula Gilbert Matsabisa, please consult his official university profile and professional network. These resources offer detailed information on his publications, projects, and ongoing contributions to the field of pharmacology and Indigenous Knowledge Systems.

Official Profile at the University of the Free State: View Academic Profile

LinkedIn Profile: Connect on LinkedIn

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